A claimant can establish duty and breach and still recover nothing if the connection between fault and harm cannot be made out. This chapter begins with the but-for test for factual causation, before turning to the modified approaches — material contribution to damage and material increase in risk — and the narrow scope for recovering a lost chance. It then moves to legal causation: the remoteness test, the eggshell skull rule that takes the claimant as found, and the intervening acts capable of breaking the chain. It closes with the position where more than one defendant is responsible, covering divisible and indivisible harm and how contribution is allocated between those liable.